Description
Melphalan is an orally available phenylalanine derivative of nitrogen mustard with antineoplastic activity. Melphalan alkylates DNA at the N7 position of guanine and induces DNA inter-strand cross-linkages, resulting in the inhibition of DNA and RNA synthesis and cytotoxicity against both dividing and non-dividing tumor cells.
Product information
CAS Number: 148-82-3
Molecular Weight: 305.20
Formula: C13H18Cl2N2O2
Synonym:
Alkeran
Sarcolysin
L-PAM
Chemical Name: (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid
Smiles: N[C@@H](CC1C=CC(=CC=1)N(CCCl)CCCl)C(O)=O
InChiKey: SGDBTWWWUNNDEQ-LBPRGKRZSA-N
InChi: InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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