Description
OTS447 is a potent FLT3 inhibitor with an IC50 of 21 nM (WO2012016082A1, compound 335).
Product information
CAS Number: 1356943-67-3
Molecular Weight: 466.01
Formula: C27H32ClN3O2
Smiles: CC(=O)C1=CN=C2C=CC(=CC2=C1NC1CCC(CC1)N(CC)CC)C1=CC(Cl)=C(O)C=C1
InChiKey: OSRDFHWWFIEYDB-UHFFFAOYSA-N
InChi: InChI=1S/C27H32ClN3O2/c1-4-31(5-2)21-10-8-20(9-11-21)30-27-22-14-18(19-7-13-26(33)24(28)15-19)6-12-25(22)29-16-23(27)17(3)32/h6-7,12-16,20-21,33H,4-5,8-11H2,1-3H3,(H,29,30)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Yo Matsuo, et al. Quinoline derivatives and melk inhibitors containing the same. WO2012016082A1.
Products are for research use only. Not for human use.
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