GANT 58

GANT58 is a cell-permeable tetrapyridinylthiophene compound that acts as downstream Hedgehog (Hh) pathway blocker and targets Gli-mediated gene transactivation (IC50 ~ 5 µM in SAG-stimulated Shh-L2 cells).

Product information

CAS Number: 64048-12-0

Molecular Weight: 392.48

Formula: C24H16N4S

Synonym:

NSC 75503

GANT58

GANT-58

NSC-75503

Chemical Name: 4-[3,4,5-tris(pyridin-4-yl)thiophen-2-yl]pyridine

Smiles: C1=CN=CC=C1C1SC(=C(C=1C1C=CN=CC=1)C1C=CN=CC=1)C1C=CN=CC=1

InChiKey: USWLOKMMUTWFMD-UHFFFAOYSA-N

InChi: InChI=1S/C24H16N4S/c1-9-25-10-2-17(1)21-22(18-3-11-26-12-4-18)24(20-7-15-28-16-8-20)29-23(21)19-5-13-27-14-6-19/h1-16H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.