Description
ACY-775 is a potent and selective histone deacetylase 6 (HDAC6) inhibitor with IC50 of 7.5 nM.
Product information
CAS Number: 1375466-18-4
Molecular Weight: 330.36
Formula: C17H19FN4O2
Chemical Name: 2-((1-(3-Fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide
Smiles: ONC(=O)C1C=NC(NC2(CCCCC2)C2=CC=CC(F)=C2)=NC=1
InChiKey: IYBURCQQEUNLDL-UHFFFAOYSA-N
InChi: InChI=1S/C17H19FN4O2/c18-14-6-4-5-13(9-14)17(7-2-1-3-8-17)21-16-19-10-12(11-20-16)15(23)22-24/h4-6,9-11,24H,1-3,7-8H2,(H,22,23)(H,19,20,21)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 66 mg/mL(199.78 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Jeanine Jochems, et al. Neuropsychopharmacology. 2014 Jan;39(2):389-400.
Products are for research use only. Not for human use.
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