CDK9-IN-10

CDK9-IN-10 is a potent CDK9 inhibitor. CDK9-IN-10 is the ligand for the PROTAC CDK9 degrader-2 (HY-112811).

Product information

CAS Number: 3542-63-0

Molecular Weight: 360.36

Formula: C22H16O5

Chemical Name: 7-(benzyloxy)-5, 8-dihydroxy-2-phenyl-4H-chromen-4-one

Smiles: OC1=C2OC(=CC(=O)C2=C(O)C=C1OCC1C=CC=CC=1)C1C=CC=CC=1

InChiKey: OQHAZMRRNANBMN-UHFFFAOYSA-N

InChi: InChI=1S/C22H16O5/c23-16-11-18(15-9-5-2-6-10-15)27-22-20(16)17(24)12-19(21(22)25)26-13-14-7-3-1-4-8-14/h1-12,24-25H,13H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Bian J, et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.

Products are for research use only. Not for human use.