CB 300919


Catalog No. Size PriceQuantity
M10729-2 Solid 2 mg $150
M10729-10 Solid 10 mg $450

Description

CB-300919 is water-soluble analogue of CB30865. It is a potential therapy for ovarian cancer. Preclinical data showed that CB 300919 has a continuous exposure (96 h) growth inhibition IC50 value of 2 nM in human CH1 ovarian tumor xenograft.

Product information

CAS Number: 289715-28-2

Molecular Weight: 584.11

Formula: C32H34ClN7O2

Chemical Name: 4-[({7-chloro-3-methyl-2-[(4-methylpiperazin-1-yl)methyl]-4-oxo-3,4-dihydroquinazolin-6-yl}methyl)(prop-2-yn-1-yl)amino]-N-[(pyridin-3-yl)methyl]benzamide

Smiles: CN1CCN(CC2=NC3=CC(Cl)=C(CN(CC#C)C4C=CC(=CC=4)C(=O)NCC4=CN=CC=C4)C=C3C(=O)N2C)CC1

InChiKey: LWTCFUSGPRGUBX-UHFFFAOYSA-N

InChi: InChI=1S/C32H34ClN7O2/c1-4-12-40(26-9-7-24(8-10-26)31(41)35-20-23-6-5-11-34-19-23)21-25-17-27-29(18-28(25)33)36-30(38(3)32(27)42)22-39-15-13-37(2)14-16-39/h1,5-11,17-19H,12-16,20-22H2,2-3H3,(H,35,41)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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