Description
PROTAC ERa Y537S dearader-1 comprises a ubiauitin E3 liaase binding aroup a linker and a protein binding aroup PROTAC ERa Y537S degrader-1 extracts from patent WO2021143822, example 12. PROTAC ERa Y537S degrader-1 is an estrogen receptor-alpha (ERa) Y537S degrader 1
Product information
CAS Number: 2667598-05-0
Molecular Weight: 767.91
Formula: C46H49N5O6
Smiles: OC1=CC2CC[C@H]([C@H](C=2C=C1)C1C=CC(=CC=1)N1CCC(CN2CCN(CC2)C2=CC3CN(C4CCC(=O)NC4=O)C(=O)C=3C3OCOC=32)CC1)C1C=CC=CC=1
InChiKey: RDRZVFBEEZKQOM-AZHZZFPQSA-N
InChi: InChI=1S/C46H49N5O6/c52-35-11-13-37-32(24-35)8-12-36(30-4-2-1-3-5-30)41(37)31-6-9-34(10-7-31)49-18-16-29(17-19-49)26-48-20-22-50(23-21-48)39-25-33-27-51(38-14-15-40(53)47-45(38)54)46(55)42(33)44-43(39)56-28-57-44/h1-7,9-11,13,24-25,29,36,38,41,52H,8,12,14-23,26-28H2,(H,47,53,54)/t36-,38?,41+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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