Description
4μ8C, also known as IRE1 Inhibitor III, is a IRE1 Inhibitor. 4µ8C inhibits IRE1α splicing of Xbp1 mRNA (IC50 = 6.8 µM) and reduces subsequent gene expression of Erdj4 (IC50 = 3.4 µM) in stress-cultured MEF cells but does not block IRE1α autophosphorylation.
Product information
CAS Number: 98-92-0
Molecular Weight: 122.12
Formula: C6H6N2O
Chemical Name: pyridine-3-carboxamide
Smiles: NC(=O)C1C=CC=NC=1
InChiKey: DFPAKSUCGFBDDF-UHFFFAOYSA-N
InChi: InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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