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Items 1 to 10 of 27 total

  1. BMS-708163 (Avagacestat), γ-Secretase Inhibitor

    Catalog No. M60032
    A potent γ-secretase Inhibitor, more selective for APP than Notch, in clinical trials for Alzheimer's disease.
  2. C646, p300/CBP inhibitor

    Catalog No. M60129
    A potent, selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor.
  3. CTEP, mGlu5 Antagonist

    Catalog No. M60099
    A highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor.
  4. DAPT, γ-secretase Inhibitor

    Catalog No. M60023
    A γ-secretase inhibitor and widely used as a Notch pathway inhibitor.
  5. HG-10-102-01, LRRK2 Inhibitor

    Catalog No. M60061
    A brain penetrant potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant.
  6. ISRIB (trans-isomer), Inhibitor of “Integrated Stress Response” (ISR)

    Catalog No. M60125
    A potent and selective small molecule inhibitor of PERK signaling that can potently reverse the effects of eIF2α phosphorylation, Inhibitor of “Integrated Stress Response” (ISR).
  7. ISX9, Neurogenic Modulator

    Catalog No. M60274
    A neurogenic modulator.
  8. J147, Neuroprotective Small Molecule

    Catalog No. M60012
    A potent and orally active neurotrophic molecule with broadly neuroprotective efficacy in vitro and in vivo.
  9. KL001, Cryptochrome Activator

    Catalog No. M66044
    A novel small molecule specifically interacting with cryptochrome (CRY) and causing lengthening of the circadian period.
  10. LY411575, γ-secretase Inhibitor

    Catalog No. M60078
    A highly potent, selective, and orally bioavailable inhibitor of gamma secretase.
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