(S)-CFT7455


Catalog No. Size PriceQuantity
M33678-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

(S)-CFT7455 is an orally active zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3) degrader. (S)-CFT7455 is an anti-cancer agent that binds with high affinity to the cereblon E3 ligase (Kd of 0.9 nM)(WO2022032132A1; Compound 1).

Product information

CAS Number: 2504235-67-8

Molecular Weight: 469.53

Formula: C28H27N3O4

Smiles: O=C1CC[C@@H](C(=O)N1)N1C2=CC=C(CC3=CC=C(CN4CCOCC4)C=C3)C3=CC=CC(=C23)C1=O

InChiKey: MUKCJOOKCZSQNW-DEOSSOPVSA-N

InChi: InChI=1S/C28H27N3O4/c32-25-11-10-24(27(33)29-25)31-23-9-8-20(21-2-1-3-22(26(21)23)28(31)34)16-18-4-6-19(7-5-18)17-30-12-14-35-15-13-30/h1-9,24H,10-17H2,(H,29,32,33)/t24-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. David Proia, et al. Advantageous therapies for disorders mediated by ikaros or aiolos. WO2022032132A1.

Products are for research use only. Not for human use.

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