2-Acetyl-4-tetrahydroxybutyl imidazole

2-Acetyl-5-tetrahydroxybutyl imidazole is a potent sphingosine-1-phosphate (S1P) lyase inhibitor in vivo.

Product information

CAS Number: 94944-70-4

Molecular Weight: 230.22

Formula: C9H14N2O5

Smiles: CC(=O)C1NC(=CN=1)[C@@H](O)[C@H](O)[C@H](O)CO

InChiKey: CQSIXFHVGKMLGQ-BWZBUEFSSA-N

InChi: InChI=1S/C9H14N2O5/c1-4(13)9-10-2-5(11-9)7(15)8(16)6(14)3-12/h2,6-8,12,14-16H,3H2,1H3,(H,10,11)/t6-,7-,8-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders . Med. Chem., 2009, 52 (13), pp 3941-3953
2. Schwab SR, et al. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science. 2005 Sep 9;309(5741):1735-9.

Products are for research use only. Not for human use.