Description
111-Trifluoroethyl-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1817735-35-5
Molecular Weight: 301.26
Formula: C10H18F3N3O4
Chemical Name: 14-azido-1,1,1-trifluoro-3,6,9,12-tetraoxatetradecane
Smiles: [N-]=[N+]=NCCOCCOCCOCCOCC(F)(F)F
InChiKey: BHMFBNPYALGJKL-UHFFFAOYSA-N
InChi: InChI=1S/C10H18F3N3O4/c11-10(12,13)9-20-8-7-19-6-5-18-4-3-17-2-1-15-16-14/h1-9H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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