MM 11253


Catalog No. Size PriceQuantity
M22800-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

MM-11253 is a synthetic, conformationally restricted retinoid that acts as a selective antagonist of retinoic acid receptor γ (RARγ).1 It dose-dependently blocks the ability of RARγ-selective agonists, but not retinoic acid (all-trans retinoic acid; to inhibit the growth of oral squamous cell carcinoma cells in vitro.

Product information

CAS Number: 345952-44-5

Molecular Weight: 462.67

Formula: C28H30O2S2

Chemical Name: 6-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dithiolan-2-yl]naphthalene-2-carboxylic acid

Smiles: CC1(C)CCC(C)(C)C2=CC(=CC=C12)C1(SCCS1)C1C=C2C=CC(=CC2=CC=1)C(O)=O

InChiKey: DPVGXUNWCVEIGT-UHFFFAOYSA-N

InChi: InChI=1S/C28H30O2S2/c1-26(2)11-12-27(3,4)24-17-22(9-10-23(24)26)28(31-13-14-32-28)21-8-7-18-15-20(25(29)30)6-5-19(18)16-21/h5-10,15-17H,11-14H2,1-4H3,(H,29,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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