Catalog No. Size PriceQuantity
M11433-2 2mg solid $120
M11433-10 10mg solid $360


ZYN57939 is RNA polymerase I inhibitor for treating RNA polymerase I-​mediated diseases. ZYN57939 was first reported in CN 104177379 A 20141203 (2014). ZYN57939 showed inhibitory activity with IC50 of 0.855 μM against human HT-​29 cancer cell lines.

Product information

CAS Number: 1639357-93-9

Molecular Weight: 524.64

Formula: C29H28N6O2S

Chemical Name: 2-((3aR, 6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4, 5]thiazolo[3, 2-a][1, 8]naphthyridine-6-carboxamide

Smiles: CN1C[C@@H]2CC(C[C@@H]2C1)C1=CC=C2C(=N1)N1C(SC3=CC=CC=C13)=C(C2=O)C(=O)NCC1=CN=C(C)C=N1


InChi: InChI=1S/C29H28N6O2S/c1-16-11-31-20(12-30-16)13-32-28(37)25-26(36)21-7-8-22(17-9-18-14-34(2)15-19(18)10-17)33-27(21)35-23-5-3-4-6-24(23)38-29(25)35/h3-8,11-12,17-19H,9-10,13-15H2,1-2H3,(H,32,37)/t17?,18-,19+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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