NSC 15364


Catalog No. Size PriceQuantity
M12526-2 2mg solid $90
M12526-10 10mg solid $270

Description

NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis.

Product information

CAS Number: 4550-72-5

Molecular Weight: 242.28

Formula: C13H14N4O

Chemical Name: 1, 3-bis(4-aminophenyl)urea

Smiles: NC1C=CC(=CC=1)NC(=O)NC1C=CC(N)=CC=1

InChiKey: MAPWYRGGJSHAAU-UHFFFAOYSA-N

InChi: InChI=1S/C13H14N4O/c14-9-1-5-11(6-2-9)16-13(18)17-12-7-3-10(15)4-8-12/h1-8H,14-15H2,(H2,16,17,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (515.93 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Mitochondrial membrane protein voltage-dependent anion channel 1 (VDAC1) oligomerization represents a prime target for agents designed to modulate apoptosis.

References:

  1. Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.

Products are for research use only. Not for human use.

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