m-PEG5-azide


Catalog No. Size PriceQuantity
M13094-2 Contact sales@xcessbio.com for quotation $100
M13094-10 Contact sales@xcessbio.com for quotation $100

Description

m-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 1202681-04-6

Molecular Weight: 277.32

Formula: C11H23N3O5

Chemical Name: 16-azido-2,5,8,11,14-pentaoxahexadecane

Smiles: COCCOCCOCCOCCOCCN=[N+]=[N-]

InChiKey: GRQHYZOCCBXIMP-UHFFFAOYSA-N

InChi: InChI=1S/C11H23N3O5/c1-15-4-5-17-8-9-19-11-10-18-7-6-16-3-2-13-14-12/h2-11H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

References:

  1. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Products are for research use only. Not for human use.

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