Description
TMP778 is a potent and selective RORγt inhibitor that suppresses experimental autoimmune uveitis development, but affects both Th17 and Th1 cell populations.
Product information
CAS Number: 1422171-08-1
Molecular Weight: 494.58
Formula: C31H30N2O4
Chemical Name: 2-[2-[(3, 5-dimethyl-1, 2-oxazol-4-yl)-hydroxymethyl]-1-benzofuran-5-yl]-N-[(R)-(2, 4-dimethylphenyl)-phenylmethyl]acetamide
Smiles: CC1C=C(C)C=CC=1[C@@H](NC(=O)CC1C=C2C=C(OC2=CC=1)C(O)C1C(C)=NOC=1C)C1=CC=CC=C1
InChiKey: DIURRJOJDQOMFC-FSRLHOSWSA-N
InChi: InChI=1S/C31H30N2O4/c1-18-10-12-25(19(2)14-18)30(23-8-6-5-7-9-23)32-28(34)16-22-11-13-26-24(15-22)17-27(36-26)31(35)29-20(3)33-37-21(29)4/h5-15,17,30-31,35H,16H2,1-4H3,(H,32,34)/t30-,31?/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Solubility (25°C). 99 mg/mL. Insoluble.
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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