β-Melanocyte Stimulating Hormone (MSH), human TFA


Catalog No. Size PriceQuantity
M13739-2 Contact sales@xcessbio.com for quotation $100

Description

β-Melanocyte Stimulating Hormone (MSH), human TFA, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor (MC4-R) agonist.

Product information

Molecular Weight: 2774.94

Formula: C120H175F3N34O37S

Chemical Name: 2, 2, 2-trifluoroacetic acid compound with 4-(2-(2-(17-((1H-imidazol-4-yl)methyl)-8-((1H-indol-3-yl)methyl)-1-(2-(2-(6-amino-1-(1, 2-dicarboxyethylamino)-1-oxohexan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)pyrrolidin-1-yl)-14-benzyl-20-(2-carboxyethyl)-11, 26-bis(3-guanidinopropyl)-2-(hydroxymethyl)-30-(4-hydroxyphenyl)-23-(2-(methylthio)ethyl)-1, 4, 7, 10, 13, 16, 19, 22, 25, 28-decaoxo-3, 6, 9, 12, 15, 18, 21, 24, 27-nonaazatriacontan-29-ylcarbamoyl)pyrrolidin-1-yl)-2-oxoethylcarbamoyl)-10, 13-bis(4-aminobutyl)-16-(2-aminopropanamido)-7-(carboxymethyl)-6, 9, 12, 15-tetraoxo-5, 8, 11, 14-tetraazanonadecane-1, 19-dioic acid

Smiles: CC(N)C(=O)NC(CCC(O)=O)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(O)=O)C(=O)NC(CCC(O)=O)C(=O)NCC(=O)N1CCCC1C(=O)NC(CC1C=CC(O)=CC=1)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCSC)C(=O)NC(CCC(O)=O)C(=O)NC(CC1=CNC=N1)C(=O)NC(CC1C=CC=CC=1)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)NC(CO)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)NC(CC(O)=O)C(O)=O.OC(=O)C(F)(F)F

InChiKey: BWWPQKDNHLLGHX-UHFFFAOYSA-N

InChi: InChI=1S/C118H174N34O35S.C2HF3O2/c1-63(122)97(167)135-77(36-39-93(159)160)105(175)137-71(23-8-11-42-119)100(170)136-72(24-9-12-43-120)102(172)147-84(55-95(163)164)111(181)140-76(35-38-92(157)158)98(168)132-60-91(156)150-47-16-28-87(150)112(182)148-81(52-65-31-33-68(154)34-32-65)109(179)138-74(26-14-45-128-117(123)124)101(171)142-79(41-50-188-2)107(177)141-78(37-40-94(161)162)106(176)146-83(54-67-58-127-62-133-67)110(180)144-80(51-64-19-4-3-5-20-64)108(178)139-75(27-15-46-129-118(125)126)103(173)145-82(53-66-57-130-70-22-7-6-21-69(66)70)99(169)131-59-90(155)134-86(61-153)114(184)152-49-18-30-89(152)115(185)151-48-17-29-88(151)113(183)143-73(25-10-13-44-121)104(174)149-85(116(186)187)56-96(165)166;3-2(4,5)1(6)7/h3-7,19-22,31-34,57-58,62-63,71-89,130,153-154H,8-18,23-30,35-56,59-61,119-122H2,1-2H3,(H,127,133)(H,131,169)(H,132,168)(H,134,155)(H,135,167)(H,136,170)(H,137,175)(H,138,179)(H,139,178)(H,140,181)(H,141,177)(H,142,171)(H,143,183)(H,144,180)(H,145,173)(H,146,176)(H,147,172)(H,148,182)(H,149,174)(H,157,158)(H,159,160)(H,161,162)(H,163,164)(H,165,166)(H,186,187)(H4,123,124,128)(H4,125,126,129);(H,6,7)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

β-Melanocyte Stimulating Hormone (MSH), human (β-MSH) has high affinity at both human MC4-R transfected into CHO cells (Ki=11.4±0.4 nM) and MC4-R in rat hypothalamic homogenates (Ki=5.0±0.4 nM).

Products are for research use only. Not for human use.

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