Catalog No. Size PriceQuantity
M21725-C Contact sales@xcessbio.com for quotation $100Unavailable


O-2050 is a high affinity cannabinoid CB1 receptor antagonist with a Ki of 2.5 nM. O-2050 inhibits cannabinoid CB2 receptor (Ki=0.2 nM). O-2050 can cause locomotor stimulation in mice.

Product information

CAS Number: 1883545-42-3

Molecular Weight: 417.56

Formula: C23H31NO4S

Chemical Name: N-{6-[(6aR,10aS)-1-hydroxy-6,6,9-trimethyl-6H,6aH,7H,10H,10aH-benzo[c]isochromen-3-yl]hex-4-yn-1-yl}methanesulfonamide

Smiles: CC1C[C@H]2[C@@H](CC=1)C(C)(C)OC1=CC(CC#CCCCNS(C)(=O)=O)=CC(O)=C12


InChi: InChI=1S/C23H31NO4S/c1-16-10-11-19-18(13-16)22-20(25)14-17(15-21(22)28-23(19,2)3)9-7-5-6-8-12-24-29(4,26)27/h10,14-15,18-19,24-25H,6,8-9,11-13H2,1-4H3/t18-,19+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

O-2050 (1, 3, 10, 30 mg/kg; ip; pretreatment 30 mins) produces significant and dose-dependent decreases in food intake in mice. O-2050 (10, 30 mg/kg) significantly causes locomotor stimulation.

Products are for research use only. Not for human use.

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