N-Benzylacetamidine (hydrobromide)

Catalog No. Size PriceQuantity
M22388-C Contact sales@xcessbio.com for quotation $100Unavailable


IC50: 0.20 μM: inhibits inducible nitric oxide synthases (iNOS). IC50: 350 μM: blocks endothelial nitric oxide synthases (eNOS). N-Benzylacetamidine is a potent and selective inhibitor of iNOS compared to eNOS. NOS is essential to the formation of nitric oxide (NO) via the NADPH- and O2-dependent oxidation of L-arginine, which plays a role in regulating many pathological and physiological processes, including smooth muscle relaxation and neurotransmission. INOS contributes to immune response and inflammation while eNOS plays a vital role in regulating vascular tone. In vitro: N-Benzylacetamidine showed good iNOS and almost negligible eNOS inhibition in THP-1 cells, a human myelomonocytic leukemia cell line . In vivo: Up to now, in vivo study of N-Benzylacetamidine is still in the development stage.

Product information

CAS Number: 186545-76-6

Molecular Weight: 229.12

Formula: C9H13BrN2

Chemical Name: N-benzylethanimidamide hydrobromide

Smiles: Br.CC(=N)NCC1C=CC=CC=1


InChi: InChI=1S/C9H12N2.BrH/c1-8(10)11-7-9-5-3-2-4-6-9;/h2-6H,7H2,1H3,(H2,10,11);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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