PAR 4 (1-6)


Catalog No. Size PriceQuantity
M22688-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

N-terminal fragment of protease-activated receptor 4 (PAR4) that acts as a PAR4 agonist (EC50 ~ 100 μM). Induces platelet aggregation and annexin V activation with no effect on clotting time. Mimics thrombin-induced increases in IL-8/CXCL8-Luc activity an

Product information

CAS Number: 225779-44-2

Molecular Weight: 619.67

Formula: C28H41N7O9

Chemical Name: (2S)-2-[(Z)-[(2S)-2-[(Z)-{2-[(Z)-{[(2S)-1-[(2S)-2-[(Z)-(2-amino-1-hydroxyethylidene)amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino]-1-hydroxyethylidene}amino]-1-hydroxy-4-(C-hydroxycarbonimidoyl)butylidene]amino]-3-methylbutanoic acid

Smiles: CC(C)[C@H](/N=C(\O)/[C@H](CCC(=N)O)/N=C(\O)/C/N=C(\O)/[C@@H]1CCCN1C(=O)[C@H](CC1=CC=C(O)C=C1)/N=C(\O)/CN)C(O)=O

InChiKey: VTCFYKYDKDAJKZ-XHOYROJHSA-N

InChi: InChI=1S/C28H41N7O9/c1-15(2)24(28(43)44)34-25(40)18(9-10-21(30)37)32-23(39)14-31-26(41)20-4-3-11-35(20)27(42)19(33-22(38)13-29)12-16-5-7-17(36)8-6-16/h5-8,15,18-20,24,36H,3-4,9-14,29H2,1-2H3,(H2,30,37)(H,31,41)(H,32,39)(H,33,38)(H,34,40)(H,43,44)/t18-,19-,20-,24-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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