{"product_id":"m23464","title":"Rhodopsin peptide","description":"\u003cp style=\"padding-left: 1em;\"\u003eRhodopsin peptide,(C51H88N14O20), a peptide with the sequence H2N-Val-Ser-Lys-Thr-Glu-Thr-Ser-Gln-Val-Ala-Pro-Ala-OH, MW= 1217.33. Rhodopsin, also known as visual purple, is a biological pigment in photoreceptor cells of the retina that is responsible for the first events in the perception of light. Rhodopsins belong to the G-protein-coupled receptor family and are extremely sensitive to light1. Mutation of the rhodopsin gene is a major contributor to various retinopathies such as retinitis pigmentosa. In general, the disease-causing protein aggregates with ubiquitin in inclusion bodies, disrupts the intermediate filament network, and impairs the ability of the cell to degrade non-functioning proteins, which leads to photoreceptor apoptosis2. Other mutations on rhodopsin lead to X-linked congenital stationary night blindness, mainly due to constitutive activation, when the mutations occur around the chromophore binding pocket of rhodopsin. Several other pathological states relating to rhodopsin have been discovered including poor post-Golgi trafficking, dysregulative activation, rod outer segment instability and arrestin binding3.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 1217.33\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormula:\u003c\/strong\u003e C51H88N14O20\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eChemical Name:\u003c\/strong\u003e 4-(2-{6-amino-2-[2-(2-amino-3-methylbutanamido)-3-hydroxypropanamido]hexanamido}-3-hydroxybutanamido)-4-({1-[(1-{[3-carbamoyl-1-({1-[(1-{2-[(1-carboxyethyl)carbamoyl]pyrrolidin-1-yl}-1-oxopropan-2-yl)carbamoyl]-2-methylpropyl}carbamoyl)propyl]carbamoyl}-2-hydroxyethyl)carbamoyl]-2-hydroxypropyl}carbamoyl)butanoic acid\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eSmiles:\u003c\/strong\u003e CC(C)C(NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(N)C(C)C)C(C)O)C(C)O)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C)C(O)=O\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eInChiKey:\u003c\/strong\u003e TWBKYVFJTVRQCD-UHFFFAOYSA-N\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eInChi:\u003c\/strong\u003e InChI=1S\/C51H88N14O20\/c1-22(2)36(54)46(79)60-31(20-66)43(76)57-28(12-9-10-18-52)40(73)63-38(26(7)68)48(81)59-30(15-17-35(71)72)42(75)64-39(27(8)69)49(82)61-32(21-67)44(77)58-29(14-16-34(53)70)41(74)62-37(23(3)4)47(80)55-24(5)50(83)65-19-11-13-33(65)45(78)56-25(6)51(84)85\/h22-33,36-39,66-69H,9-21,52,54H2,1-8H3,(H2,53,70)(H,55,80)(H,56,78)(H,57,76)(H,58,77)(H,59,81)(H,60,79)(H,61,82)(H,62,74)(H,63,73)(H,64,75)(H,71,72)(H,84,85)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTechnical Data\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAppearance:\u003c\/strong\u003e Solid Power\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (or refer to the Certificate of Analysis)\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eShipping Condition:\u003c\/strong\u003e Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eStorage Condition:\u003c\/strong\u003e Dry, dark and -20 \u003csup\u003eo\u003c\/sup\u003eC for 1 year or refer to the Certificate of Analysis.\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eShelf Life:\u003c\/strong\u003e ≥12 months if stored properly.\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eStock Solution Storage:\u003c\/strong\u003e 0 - 4 \u003csup\u003eo\u003c\/sup\u003eC for 1 month or refer to the Certificate of Analysis.\u003c\/p\u003e\n\u003cp style=\"text-indent: -1em; padding-left: 1em;\"\u003e\u003cstrong\u003eDrug Formulation:\u003c\/strong\u003e To be determined\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHS Tariff Code:\u003c\/strong\u003e 382200\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProducts are for research use only. Not for human use.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Xcess Biosciences","offers":[{"title":"M23464-C \/ Contact sales@xcessbio.com for quotation","offer_id":39528220459147,"sku":"0","price":100.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0389\/1897\/9723\/files\/1686726650496.png?v=1686726671","url":"https:\/\/www.xcessbio.com\/products\/m23464","provider":"Xcess Biosciences","version":"1.0","type":"link"}