Mal-PEG3-alcohol


Catalog No. Size PriceQuantity
M23550-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Mal-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 146551-23-7

Molecular Weight: 229.23

Formula: C10H15NO5

Chemical Name: 1-{2-[2-(2-hydroxyethoxy)ethoxy]ethyl}-2,5-dihydro-1H-pyrrole-2,5-dione

Smiles: OCCOCCOCCN1C(=O)C=CC1=O

InChiKey: DRANPRSEAZUMPF-UHFFFAOYSA-N

InChi: InChI=1S/C10H15NO5/c12-4-6-16-8-7-15-5-3-11-9(13)1-2-10(11)14/h1-2,12H,3-8H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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