Description
Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis.
Product information
CAS Number: 487-36-5
Molecular Weight: 358.39
Formula: C20H22O6
Chemical Name: 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxyphenyl)-hexahydrofuro[3,4-c]furan-1-yl]-2-methoxyphenol
Smiles: COC1C=C(C=CC=1O)[C@H]1OC[C@@H]2[C@H](OC[C@@H]21)C1C=C(OC)C(O)=CC=1
InChiKey: HGXBRUKMWQGOIE-AFHBHXEDSA-N
InChi: InChI=1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (279.03 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Pinoresinol facilitated death-inducing signaling complex formation to trigger a caspase-8-dependent apoptotic cascade activation in TRAIL-resistant glioblastoma cells.
Products are for research use only. Not for human use.
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