Loxapine-d8 hydrochloride

Catalog No. Size PriceQuantity
M23783-C Contact sales@xcessbio.com for quotation $100Unavailable


Loxapine-d8 hydrochloride is the deuterium labeled Loxapine. Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.

Product information

CAS Number: 1246820-19-8

Molecular Weight: 372.32

Formula: C18H19Cl2N3O

Chemical Name: 13-chloro-10-[4-methyl(2,2,3,3,5,5,6,6-²H₈)piperazin-1-yl]-2-oxa-9-azatricyclo[³,⁸]pentadeca-1(15),3,5,7,9,11,13-heptaene hydrochloride

Smiles: Cl.[2H]C1([2H])N(C)C([2H])([2H])C([2H])([2H])N(C2=NC3=CC=CC=C3OC3=CC=C(Cl)C=C32)C1([2H])[2H]


InChi: InChI=1S/C18H18ClN3O.ClH/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18;/h2-7,12H,8-11H2,1H3;1H/i8D2,9D2,10D2,11D2;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

Products are for research use only. Not for human use.

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