Catalog No. Size PriceQuantity
M24058-C Contact for quotation $100Unavailable


MLT-747 is a potent, selective, allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 14 nM.

Product information

CAS Number: 2097853-86-4

Molecular Weight: 478.33

Formula: C20H21Cl2N7O3

Chemical Name: 1-[5-chloro-6-(pyrrolidine-1-carbonyl)pyridin-3-yl]-3-{2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl}urea

Smiles: CO[C@@H](C)C1=C(C=NC2=CC(Cl)=NN21)NC(=O)NC1=CN=C(C(Cl)=C1)C(=O)N1CCCC1


InChi: InChI=1S/C20H21Cl2N7O3/c1-11(32-2)18-14(10-23-16-8-15(22)27-29(16)18)26-20(31)25-12-7-13(21)17(24-9-12)19(30)28-5-3-4-6-28/h7-11H,3-6H2,1-2H3,(H2,25,26,31)/t11-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

MLT-747 (0-20 μM) stabilizes cellular MALT1-W580S with an EC50 of 314 nM.

Products are for research use only. Not for human use.

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