Description
BAY-524 is a Bub1 inhibitor, with an IC50 of 450 nM for human Bub1 in the presence of 2 mM ATP.
Product information
CAS Number: 1445830-39-6
Molecular Weight: 482.48
Formula: C24H24F2N6O3
Chemical Name: 2-{1-[(4-ethoxy-2,6-difluorophenyl)methyl]-5-methoxy-4-methyl-1H-pyrazol-3-yl}-5-methoxy-N-(pyridin-4-yl)pyrimidin-4-amine
Smiles: CC1C(=NN(CC2C(F)=CC(=CC=2F)OCC)C=1OC)C1=NC(NC2C=CN=CC=2)=C(C=N1)OC
InChiKey: LMRCQVHTZUUHFN-UHFFFAOYSA-N
InChi: InChI=1S/C24H24F2N6O3/c1-5-35-16-10-18(25)17(19(26)11-16)13-32-24(34-4)14(2)21(31-32)23-28-12-20(33-3)22(30-23)29-15-6-8-27-9-7-15/h6-12H,5,13H2,1-4H3,(H,27,28,29,30)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 166.67 mg/mL (345.44 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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