{"product_id":"m33490","title":"Peptide 78","description":"\u003cp style=\"padding-left:1em;\"\u003ePeptide 78 identical to peptide 74 except that serine replaces cysteine; does not inhibit 72-kDa type IV collagenase. Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA)\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eProduct information\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 132116-62-2\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 1487.68\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFormula:\u003c\/strong\u003e C60H106N22O20S\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eChemical Name:\u003c\/strong\u003e (3S)-3-{[(2S)-1-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S, 3R)-2-amino-3-hydroxybutanamido]-4-(methylsulfanyl)butanamido]-5-carbamimidamidopentanamido]hexanamido]-5-carbamimidamidopentanamido]-3-hydroxypropanamido]acetamido}-3-carbamoylpropanoyl]pyrrolidin-2-yl]formamido}-3-{[(1S)-1-{[(1S)-1-{[(1S)-2-carbamoyl-1-carboxyethyl](propyl)carbamoyl}ethyl]carbamoyl}-2-methylpropyl]carbamoyl}propanoic acid\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eSmiles:\u003c\/strong\u003e CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N(CCC)[C@@H](CC(N)=O)C(O)=O\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eInChiKey:\u003c\/strong\u003e OPKCDFWAZKOPFX-OMBAYSRHSA-N\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eInChi:\u003c\/strong\u003e InChI=1S\/C60H106N22O20S\/c1-7-21-81(40(58(101)102)26-42(63)86)56(99)30(4)72-55(98)46(29(2)3)80-52(95)36(25-44(88)89)78-53(96)39-16-12-22-82(39)57(100)37(24-41(62)85)73-43(87)27-71-47(90)38(28-83)79-50(93)34(15-11-20-70-60(67)68)75-48(91)32(13-8-9-18-61)74-49(92)33(14-10-19-69-59(65)66)76-51(94)35(17-23-103-6)77-54(97)45(64)31(5)84\/h29-40,45-46,83-84H,7-28,61,64H2,1-6H3,(H2,62,85)(H2,63,86)(H,71,90)(H,72,98)(H,73,87)(H,74,92)(H,75,91)(H,76,94)(H,77,97)(H,78,96)(H,79,93)(H,80,95)(H,88,89)(H,101,102)(H4,65,66,69)(H4,67,68,70)\/t30-,31+,32-,33-,34-,35-,36-,37-,38-,39-,40-,45-,46-\/m0\/s1\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTechnical Data\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAppearance:\u003c\/strong\u003e Solid Power\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (or refer to the Certificate of Analysis)\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e To be determined\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eShipping Condition:\u003c\/strong\u003e Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eStorage Condition:\u003c\/strong\u003e Dry, dark and -20 \u003csup\u003eo\u003c\/sup\u003eC for 1 year or refer to the Certificate of Analysis.\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eShelf Life:\u003c\/strong\u003e ≥12 months if stored properly.\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eStock Solution Storage:\u003c\/strong\u003e 0 - 4 \u003csup\u003eo\u003c\/sup\u003eC for 1 month or refer to the Certificate of Analysis.\u003c\/p\u003e\u003cp style=\"text-indent:-1em;padding-left:1em;\"\u003e\u003cstrong\u003eDrug Formulation:\u003c\/strong\u003e To be determined\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHS Tariff Code:\u003c\/strong\u003e 382200\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHow to use\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIn Vitro:\u003c\/strong\u003e\u003c\/p\u003e\u003cp style=\"padding-left:1em;\"\u003ePeptide 78 identical to peptide 74 except that serine replaces cysteine; does not inhibit 72-kDa type IV collagenase.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\u003col style=\"padding-left:1em;\"\u003e\n\u003cli\u003eLi Z, Wang Z, Zhang C, Chen J, Su Y, Huang J, Yi Z, Yuan C, Hong W, Wang Y, Wu Z, Hu Y, Cao L, Peng D, Guan Y, Zou Y, Yu S, Cui D, Fang Y. Reduced ENA78 levels as novel biomarker for major depressive disorder and venlafaxine efficiency: Result from a prospective longitudinal study. Psychoneuroendocrinology. 2017 Jul;81:113-121. doi: 10.1016\/j.psyneuen.2017.03.015. Epub 2017 Mar 18. PubMed PMID: 28441588.\u003c\/li\u003e\n\u003cli\u003eLiu L, Chowdhury S, Fang X, Liu JL, Srikant CB. Attenuation of unfolded protein response and apoptosis by mReg2 induced GRP78 in mouse insulinoma cells. FEBS Lett. 2014 May 29;588(11):2016-24. doi: 10.1016\/j.febslet.2014.04.030. Epub 2014 May 4. PubMed PMID: 24801175.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003e\u003cstrong\u003eProducts are for research use only. Not for human use.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Xcess Biosciences","offers":[{"title":"M33490-2 \/ 2 mg solid","offer_id":39846177243275,"sku":"","price":165.0,"currency_code":"USD","in_stock":true},{"title":"M33490-10 \/ 10 mg solid","offer_id":39846177276043,"sku":"","price":520.0,"currency_code":"USD","in_stock":true},{"title":"M33490-C \/ Contact sales@xcessbio.com for quotation","offer_id":39846177308811,"sku":"","price":100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0389\/1897\/9723\/files\/1689055601780.png?v=1735786005","url":"https:\/\/www.xcessbio.com\/products\/m33490","provider":"Xcess Biosciences","version":"1.0","type":"link"}