UCN-02


Catalog No. size PriceQuantity
M6824-2 2mg solid $668
M6824-10 10mg solid $2,676

Description

Cas:121569-61-7

Product Information

UCN-02 is a stereoisomer of UCN-01 which inhibits protein kinase C with a slightly reduced potency than UCN-01.

 

Chemical Formula: C28H26N4O4

 

Exact Mass: 482.1954

 

Molecular Weight: 482.54

 

Elemental Analysis: C, 69.70; H, 5.43; N, 11.61; O, 13.26

 

Chemical Name: 18-Hydroxy-3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one

 

InChi Key:

PBCZSGKMGDDXIJ-NXNPIKFHSA-N

 

InChi Code: InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,27,29,34H,12H2,1-3H3,(H,30,33)/t15-,18-,25-,27?,28+/m0/s1

 

Smiles Code:

O=C1C(C2=C3C4=C5C6=C(N4[C@@]7(C)[C@@H](OC)[C@@H](NC)C[C@@](O7)([H])N3C8=C2C=CC=C8)C=CC=C6)=C5C(O)N1

 

 

Technical Data:

 

Appearance: A solution in ethanol

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Takahashi I, Asano K, Kawamoto I, Tamaoki T, Nakano H. UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation. J Antibiot (Tokyo). 1989 Apr;42(4):564-70. PubMed PMID: 2722672.

 

  1. Takahashi I, Saitoh Y, Yoshida M, Sano H, Nakano H, Morimoto M, Tamaoki T. UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities. J Antibiot (Tokyo). 1989 Apr;42(4):571-6. PubMed PMID: 2656615.

 

Products are for research use only. Not for human use.

 

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