Chelerythrine chloride

Catalog No. size PriceQuantity
M6838-2 2mg solid $124
M6838-10 10mg solid $494



Product Information

Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable protein kinase C inhibitor.


Chemical Formula: C21H18ClNO4


Molecular Weight: 383.82492


Elemental Analysis: C, 65.71; H, 4.73; Cl, 9.24; N, 3.65; O, 16.67





Chelerythrine chloride


Chemical Name: 1,2-dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-ium chloride


InChi Key:



InChi Code: InChI=1S/C21H18NO4.ClH/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22;/h4-10H,11H2,1-3H3;1H/q+1;/p-1


Smiles Code:




Technical Data:


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >5 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001





  1. Gao ZQ, Han BH, Sha HF, Shi ZY, Yang XH, Feng JX. [Effects of a protein kinase C inhibitor combined with cisplatin on non-small cell lung cancer.]. Zhonghua Jie He He Hu Xi Za Zhi. 2010 Apr;33(4):284-8. Chinese. PubMed PMID: 20646461.


  1. Lu DQ, Chen Y, Li T, Li BL. [Role of protein kinase C in protecting rats against pulmonary ischemia reperfusion injury through opening of mitochondrial ATP sensitive potassium channel]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 May;41(3):436-40. Chinese. PubMed PMID: 20629316.


  1. Alloatti G, Arnoletti E, Bassino E, Penna C, Perrelli MG, Ghé C, Muccioli G. Obestatin affords cardioprotection to the ischemic/reperfused isolated rat heart and inhibits apoptosis in cultures of similarly stressed cardiomyocytes. Am J Physiol Heart Circ Physiol. 2010 Jun 4. [Epub ahead of print] PubMed PMID: 20525876.


  1. Wang HJ, Jiang HL, Chen XH, Lin PY, Zhu YC, Tao LL. [The anti-apoptosis effect of erythropoietin on neonatal rat cardiocytes during hypoxia/reoxygenation injury and its possible mechanism.]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 May;22(5):302-5. Chinese. PubMed PMID: 20519083.


  1. Adão-Novaes J, de Cássia Belem Guterrres C, Linden R, Sholl-Franco A. Rod photoreceptor cell death is induced by okadaic acid through activation of PKC and L-type voltage-dependent Ca2+ channels and prevented by IGF-1. Neurochem Int. 2010 Sep;57(2):128-35. Epub 2010 May 11. PubMed PMID: 20466029.


Products are for research use only. Not for human use.



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