ID-8 inhibitor

Catalog No. size PriceQuantity
M7008-2 2mg solid $131
M7008-10 10mg solid $530



Product Information

ID-8 is a DYRK inhibitor, and sustains embryonic stem cell self-renewal in long-term culture.


Chemical Formula: C16H14N2O4


Exact Mass: 298.0954


Molecular Weight: 298.298


Elemental Analysis: C, 64.42; H, 4.73; N, 9.39; O, 21.45




ID-8 inhibitor

ID 8 inhibitor

ID8 inhibitor


Chemical Name: 



InChi Key: 



InChi Code: InChI=1S/C16H14N2O4/c1-10-16(18(20)21)14-8-5-12(19)9-15(14)17(10)11-3-6-13(22-2)7-4-11/h3-9,19H,1-2H3


Smiles Code:




Technical Data:


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


In Vitro:

ID-8 (0.1-10 μM) increases human embryonic stem cell (hESC) survival.

ID-8 (10 μM) stimulates ESCs proliferation in serum-free media for more than 1 month.





  1. Monteiro MB, Ramm S, Chandrasekaran V, Boswell SA, Weber EJ, Lidberg KA, Kelly EJ, Vaidya VS. A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation. J Am Soc Nephrol. 2018 Dec;29(12):2820-2833. doi: 10.1681/ASN.2018040392. Epub 2018 Oct 25. PMID: 30361326; PMCID: PMC6287872.


  1. Sylvain V, Lafarge S, Bignon YJ. Molecular pathways involved in response to ionizing radiation of ID-8 mouse ovarian cancer cells expressing exogenous full- length Brca1 or truncated Brca1 mutant. Int J Oncol. 2001 Sep;19(3):599-607. doi: 10.3892/ijo.19.3.599. PMID: 11494042.


Products are for research use only. Not for human use.


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