AVN-101 HCl


Catalog No. size PriceQuantity
M7083-2 2mg solid $112
M7083-10 10mg solid $441

Description

AVN-101 is a very potent 5-HT7 receptor antagonist, with slightly lesser potency toward 5-HT6, 5-HT2A, and 5HT-2C receptors. It is a milti-target drug candidate for the treatment of CNS disorders.

Product information

CAS Number: 1061354-48-0

Molecular Weight: 340.89

Formula: C21H25ClN2

Synonym:

AVN-101

AVN 101

AVN101

Chemical Name: 2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride

Smiles: Cl.CN1CC2C3=CC(C)=CC=C3N(CCC3=CC=CC=C3)C=2CC1

InChiKey: RKLJJDFIWWRTEJ-UHFFFAOYSA-N

InChi: InChI=1S/C21H24N2.ClH/c1-16-8-9-20-18(14-16)19-15-22(2)12-11-21(19)23(20)13-10-17-6-4-3-5-7-17;/h3-9,14H,10-13,15H2,1-2H3;1H

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Ivachtchenko AV, Lavrovsky Y, Okun I. AVN-101: A Multi-Target Drug Candidate for the Treatment of CNS Disorders. J Alzheimers Dis. 2016 May 25;53(2):583-620. doi: 10.3233/JAD-151146. PubMed PMID: 27232215; PubMed Central PMCID: PMC4969713.

Products are for research use only. Not for human use.

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