TG-89, inhibitor of JAK2, FLT3, RET and JAK3

Catalog No. Size PriceQuantity
M7390-2 2mg solid $200
M7390-10 10mg solid $690


TG-89 is an inhibitor of JAK2 with IC50 of 11.2 μM.

Product information

CAS Number: 936091-56-4

Molecular Weight: 510.65

Formula: C26H34N6O3S

Chemical Name: N-tert-Butyl-3-[[5-methyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide

Smiles: CC1=CN=C(NC2=CC(CN3CCOCC3)=CC=C2)N=C1NC1=CC(=CC=C1)S(=O)(=O)NC(C)(C)C


InChi: InChI=1S/C26H34N6O3S/c1-19-17-27-25(29-21-8-5-7-20(15-21)18-32-11-13-35-14-12-32)30-24(19)28-22-9-6-10-23(16-22)36(33,34)31-26(2,3)4/h5-10,15-17,31H,11-14,18H2,1-4H3,(H2,27,28,29,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C) DMSO: 10 mg/mL(19.58 mM). Water: ˂1 mg/mL.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Kirill Gorshkov, et al. Transl Oncol. 2019 Mar;12(3):441-452.

Products are for research use only. Not for human use.

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