Lucigenin

UC-781 is a non-nucleoside reverse transcriptase inhibitor potenially for the treatment of HIV infection. In human cervical explant cultures, UC-781 was not only able to inhibit direct infection of mucosal tissue but was able to prevent dissemination of virus by migratory cells. UC-781 formulated into a carbopol gel (0.1%) retained significant activity against both direct tissue infection and transinfection mediated by migratory cells. Furthermore, UC-781 demonstrated prolonged inhibitory effects able to prevent both localized and disseminated infections up to 6 days post compound treatment.

Product information

CAS Number: 2315-97-1

Molecular Weight: 510.50

Formula: C28H22N4O6

Synonym:

NSC-151912

L-6868

Chemical Name: 10,10'-dimethyl-[9,9'-biacridine]-10,10'-diium nitrate

Smiles: C[N+]1C2=CC=CC=C2C(C2C3=CC=CC=C3[N+](C)=C3C=CC=CC3=2)=C2C=CC=CC=12.[O-]N(=O)=O.[O-]N(=O)=O

InChiKey: KNJDBYZZKAZQNG-UHFFFAOYSA-N

InChi: InChI=1S/C28H22N2.2NO3/c1-29-23-15-7-3-11-19(23)27(20-12-4-8-16-24(20)29)28-21-13-5-9-17-25(21)30(2)26-18-10-6-14-22(26)28;2*2-1(3)4/h3-18H,1-2H3;;/q+2;2*-1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.