DMOG, also known as Dimethyloxaloylglycine, is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM. DMOG provides neuroprotection after traumatic brain injury. DMOG provides enhanced efficacy with reduced systemic exposure in a murine model of colitis.
CAS Number: 298-96-4
Molecular Weight: 334.80
Chemical Name: triphenyl-3H-1,2λ⁵,3,4-tetrazol-2-ylium chloride
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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