Zopiclone


Catalog No. Size PriceQuantity
M8761-2 Contact sales@xcessbio.com for quotation $100
M8761-10 Contact sales@xcessbio.com for quotation $100

Description

NOTE: Zopiclone has been discontinued | Zopiclone is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia. It is a cyclopyrrolone, which increases the normal transmission of the neurotransmitter GABA in the central nervous system, as benzodiazepines do, but in a different way. As zopiclone is sedating, it is marketed as a sleeping pill. It works by causing a depression or tranquilization of the central nervous system.

Product information

CAS Number: 43200-80-2

Molecular Weight: 388.81

Formula: C17H17ClN6O3

Synonym:

Imovane

Zimovane

RP27267

Chemical Name: 6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate

Smiles: CN1CCN(CC1)C(=O)OC1C2=NC=CN=C2C(=O)N1C1=CC=C(Cl)C=N1

InChiKey: GBBSUAFBMRNDJC-UHFFFAOYSA-N

InChi: InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Curreen M, Lidmila J. Zopiclone: Is there cause for concern in addiction services and general practice? Int J Risk Saf Med. 2014;26(4):183-9.
  2. Stranks EK, Crowe SF. The acute cognitive effects of zopiclone, zolpidem, zaleplon, and eszopiclone: a systematic review and meta-analysis. J Clin Exp Neuropsychol. 2014;36(7):691-700.
  3. Chan TY. Zopiclone induced methemoglobinemia and hemolytic anemia. Int J Clin Pharmacol Ther. 2014 May;52(5):402-6.

Products are for research use only. Not for human use.

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