Pamidronate (disodium pentahydrate)

Pamidronate disodium pentahydrate is a nitrogen-containing bisphosphonate, used to prevent osteoporosis.

Product information

CAS Number: 109552-15-0

Molecular Weight: 369.11

Formula: C3H19NNa2O12P2

Chemical Name: (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid hydrate sodium

Smiles: O.O.O.O.O.[Na+].[Na+].NCCC(O)(P([O-])(O)=O)P([O-])(O)=O

InChiKey: CZYWHNTUXNGDGR-UHFFFAOYSA-L

InChi: InChI=1S/C3H11NO7P2.2Na.5H2O/c4-2-1-3(5,12(6,7)8)13(9,10)11;;;;;;;/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11);;;5*1H2/q;2*+1;;;;;/p-2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 7.14 mg/mL (19.34 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Kubalek I, et al. Treatment of reflex sympathetic dystrophy with pamidronate: 29 cases. Rheumatology (Oxford). 2001 Dec;40(12):1394-7.
2. Zarychanski R, et al. Osteonecrosis of the jaw associated with pamidronate therapy. Am J Hematol. 2006 Jan;81(1):73-5.

Products are for research use only. Not for human use.