Luminolate is an immune modulator with SARS-CoV-2 antiviral activity via a multi-target mechanism including localized, self-limiting reactive oxygen species (ROS) scavenging activities that were demonstrated in a model of lipopolysaccharide (LPS)-induced joint inflammation, modulating PARP-1.
CAS Number: 20666-12-0
Molecular Weight: 199.14
Chemical Name: sodium 5-amino-1,4-dioxo-1,2,3,4-tetrahydrophthalazin-2-ide
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
Luminol concentration is an important factor that affects Chemiluminescence (CL) intensity. The intensity of Luminol chemiluminescence (LCL) does not depend on the concentration of Luminol alone, but also on other factors like concentration of oxidizing agents, enzymes, and pH. Maximum recorded CL intensity was at a Luminol concentration of 0.3 mM. CL intensity increased linearly with increasing concentrations of Luminol in the range of 0.01 to 0.3 mM. However, further increases of Luminol concentration caused a decrease in CL intensity.
- Michael Mayer, et al. Shedding Light on the Diversity of Surfactant Interactions with Luminol Electrochemiluminescence for Bioanalysis. Anal Chem. 2019 Oct 15;91(20):13080-13087.
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