Potent and selective histone demethylase JMJD2 inhibitor for in vivo use
Modulation of aberrant Jumonji demethylase activity in disease should lead to the normalization of transcriptional patterns. SD70 is a very good chemical tool to study a selective subset of Jumonji histone demethylases in vitro and in vivo, including stem cell and development, cancers, and neurological diseases.
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