Uropressure receptor (UT) is a G-protein-coupled receptor that binds the peptide hormone angiotensin. Uropressure-ii (UT) receptor is a Gq/11- protein-coupled receptor that mediates complex hemodynamic effects and influences neuromuscular physiology. UT receptors show maximum expression levels in the peripheral vascular system, heart, and kidney, although they are found at lower levels elsewhere, especially in the central nervous system. UT receptor produces potent but variable vasoconstriction in some vascular beds, but mediates vasodilation in others. It is also involved in osmotic regulation.