Pyruvate dehydrogenase is a complex composed of three enzymes, responsible for catalyzing the irreversible reaction of pyruvate decarboxylation to acetyl coenzyme A, distributed in the inner membrane of mitochondria. Enzymes differ from phosphorylases in that they come in inactive (phosphorylated) and active (dephosphorylated) forms. A variety of allosteric regulators regulate the conversion of the two enzyme forms and are influenced by hormonal activity.
Xcess Biosciences Inc (XcessBio or Xbio) was founded in 2008 by scientists from academia and BioPharma industry with strong expertise in chemistry and biology. We are dedicated to develop high-quality products and deliver the best services for our customers.
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