Tyrosinase, an enzyme with specificity for malignant melanoma, is regulated by the human tyrosinase promoter. Transgenes that are driven by this promoter transduce melanoma cells and have the potential to induce tumor regression. Similarly, a human tyrosinase promoter construct linked to two enhancer elements causes high-level, melanoma-specific expression of a reporter gene in transient transfection assays. The murine tyrosinase promoter-enhancer expression cassette expressed by an Adv vector has been shown to maintain transcriptional specificity for pigment cell lineages, especially human melanoma cell lines.
Xcess Biosciences Inc (XcessBio or Xbio) was founded in 2008 by scientists from academia and BioPharma industry with strong expertise in chemistry and biology. We are dedicated to develop high-quality products and deliver the best services for our customers.
Your orders will be processed within 24 hours if the requested items are available in stock. We do not ship out orders on Friday. Orders received on Friday will be shipped out in the morning of the following Monday.
We diligently develop high quality products and strive to earn your satisfaction. If for any reason you are not satisfied with your purchases, please follow our Return Policy for product return or exchange.
If you know of any technology, product, or service development opportunities in the fields related, we would be very interested in hearing from you. Please Contact Us.