The 90 kDa ribosomal S6 kinase (RSK) family of proteins is a group of highly conserved Ser/Thr kinases that regulate diverse cellular processes, such as cell growth, cell motility, cell survival and cell proliferation. RSKs are downstream effectors of the Ras-extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signalling cascade. Significant advances in the field of RSK and ERK/MAPK signalling have occurred in the past, including biological insights and the discovery of novel substrates and new RSK regulatory mechanisms. Collectively, these data expand the current models of RSK signalling and highlight potential directions of research in RSK-mediated survival, growth, proliferation and migration.
87556-03-4
From $100
AR7 --- RARα antagonist
From $55
AT7867
From $95
AT7867 dihydrochloride
From $95
BI-D1870
From $95
BIX 02565
From $110
BRD7389
From $385
CKI-7
$100
CKI-7 free base
From $125
CMK
From $90
Eudesmin
From $545
FMK
From $150
LY-2584702 free base
From $95
LY-2584702 Hydrochloride
From $90
LY-2584702 tosylate salt
From $95
PF-4708671
From $85
Pluripotin
From $110
S6K-18
From $100
SM1-71
$100
Sodium Salicylate
From $80
YS-49 monohydrate
From $80