SRPK is a family of key enzymes that regulate splicing activity in cells. The first serine-arginine (SR) protein kinase to be identified is SRPK1, which is isolated from mitotic cells and is described as phosphorylating SR proteins and promoting their release from the nuclear spot during the G2/M phase of the cell cycle. SRPK1 is the prototype of the SRPK family, which also includes two homologous SRPK2 and SRPK3 proteins. SRPK is characterized by dichotomous catalytic domains separated by unique spacer sequences and located primarily in the cytoplasm of mammalian cells. SRPK can be transferred to the nucleus under several conditions, such as during the G2/M phase of the cell cycle, or after osmotic stress, or as a result of activation of epidermal growth factor (EGF) signal transduction pathways.
Xcess Biosciences Inc (XcessBio or Xbio) was founded in 2008 by scientists from academia and BioPharma industry with strong expertise in chemistry and biology. We are dedicated to develop high-quality products and deliver the best services for our customers.
Your orders will be processed within 24 hours if the requested items are available in stock. We do not ship out orders on Friday. Orders received on Friday will be shipped out in the morning of the following Monday.
We diligently develop high quality products and strive to earn your satisfaction. If for any reason you are not satisfied with your purchases, please follow our Return Policy for product return or exchange.
If you know of any technology, product, or service development opportunities in the fields related, we would be very interested in hearing from you. Please Contact Us.