BRL 37344 sodium

BRL 37344 sodium (BRL 37344A) is a specific β3-adrenergic receptor agonist. BRL 37344 sodium treatment significantly lowers the body weight of obese mice.

Product information

CAS Number: 127299-93-8

Molecular Weight: 385.82

Formula: C19H21ClNNaO4

Synonym:

BRL 37344A

Chemical Name: sodium 2-{4-[(2S)-2-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}propyl]phenoxy}acetate

Smiles: [Na+].C[C@@H](CC1C=CC(=CC=1)OCC([O-])=O)NC[C@@H](O)C1C=C(Cl)C=CC=1

InChiKey: SNJIJYKMYQRHRC-UFRBEDTPSA-M

InChi: InChI=1S/C19H22ClNO4.Na/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24;/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24);/q;+1/p-1/t13-,18+;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

BRL37344 sodium (BRL 37344A) treatment significantly lowers the body weight of obese mice.

References:

1. Wu C, et al. Activating brown adipose tissue for weight loss and lowering of blood glucose levels: a microPET study using obese and diabetic model mice. PLoS One. 2014 Dec 2;9(12):e113742.

Products are for research use only. Not for human use.