Bornyl acetate

Bornyl acetate is a potent odorant, exhibiting one of the highest flavor dilution factor (FD factor). Bornyl acetate possesses anti-cancer activity.

Product information

CAS Number: 76-49-3

Molecular Weight: 196.29

Formula: C12H20O2

Chemical Name: (1S, 2R, 4S)-1, 7, 7-trimethylbicyclo[2.2.1]heptan-2-yl acetate

Smiles: CC1(C)[C@@H]2C[C@@H](OC(C)=O)[C@@]1(C)CC2

InChiKey: KGEKLUUHTZCSIP-HOSYDEDBSA-N

InChi: InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10,4)11(9,2)3/h9-10H,5-7H2,1-4H3/t9-,10+,12+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 83.33 mg/mL (424.52 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Bornyl acetate is characterized as one of the most important odorants of fresh ginger juice, as it exhibits one of the highest FD factors. Bornyl acetate is also identified as playing very important sensory roles in the aroma of fresh Japanese ginger. Bornyl acetate (0-96 μM) induces dose-dependent growth inhibitory efects on human gastric cancer cells in vitro. Combined effect of Bornyl acetate (48 μM) and 5-FU on SGC-7901 human gastric cancer cell death via apoptosis.

References:

1. Pang X, et al. Identification of Ginger (Zingiber officinale Roscoe) Volatiles and Localization of Aroma-Active Constituents by GC-Olfactometry. J Agric Food Chem. 2017 May 24;65(20):4140-4145.
2. Juan Li, et al. Synergistic enhancement of the antitumor activity of 5-fuorouracil by bornyl acetate in SGC-7901 human gastric cancer cells and the determination of the underlying mechanism of action. J BUON. Jan-Feb 2016;21(1):108-17.

Products are for research use only. Not for human use.