1αH, 5αH-Guaia-6-ene-4β, 10β-diol

1αH,5αH-Guaia-6-ene-4β,10β-diol is a sesquiterpenoid derivative identified from Alisma orientale. 1αH,5αH-Guaia-6-ene-4β,10β-diol has anti-cancer activities.

Product information

CAS Number: 2013537-81-8

Molecular Weight: 238.37

Formula: C15H26O2

Chemical Name: (1S,3aR,4S,8aR)-3a,8a-dihydrogenio-1,4-dimethyl-7-(propan-2-yl)-1,2,3,3a,4,5,6,8a-octahydroazulene-1,4-diol

Smiles: CC(C)C1CC[C@](C)(O)[C@@H]2CC[C@](C)(O)[C@@H]2C=1

InChiKey: IWQURBSTAIRNAE-KBXIAJHMSA-N

InChi: InChI=1S/C15H26O2/c1-10(2)11-5-7-14(3,16)12-6-8-15(4,17)13(12)9-11/h9-10,12-13,16-17H,5-8H2,1-4H3/t12-,13-,14+,15+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

1αH,5αH-Guaia-6-ene-4β,10β-diol has anti-cancer activities. 1αH,5αH-Guaia-6-ene-4β,10β-diol is against H460, MCF-7, and PC-7 with IC50s of 56.7 μM, 76.7 μM, and 59.0 μM, respectively.

References:

1. Qingjuan Ma, et al. Structures and biological activities of the triterpenoids and sesquiterpenoids from Alisma orientale. Phytochemistry

Products are for research use only. Not for human use.