cyt-PTPε Inhibitor-1


Catalog No. Size PriceQuantity
M13904-2 Contact sales@xcessbio.com for quotation $100

Description

cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity.

Product information

CAS Number: 428478-94-8

Molecular Weight: 368.45

Formula: C19H20N4O2S

Chemical Name: 3-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-1-(4-methylphenyl)urea

Smiles: CC1C=C(C)C(=CC=1)OCC1=NN=C(NC(=O)NC2C=CC(C)=CC=2)S1

InChiKey: QUSAMXSWOZSTRQ-UHFFFAOYSA-N

InChi: InChI=1S/C19H20N4O2S/c1-12-4-7-15(8-5-12)20-18(24)21-19-23-22-17(26-19)11-25-16-9-6-13(2)10-14(16)3/h4-10H,11H2,1-3H3,(H2,20,21,23,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

cyt-PTPε Inhibitor-1 (Compound 62) is a potent cytosolic protein tyrosine phosphatase epsilon with anti-osteoclastic activity.

References:

  1. Ku B, et al. Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26(18):5204-5211.

Products are for research use only. Not for human use.

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