Description
cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity.
Product information
CAS Number: 428478-94-8
Molecular Weight: 368.45
Formula: C19H20N4O2S
Chemical Name: 3-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-1-(4-methylphenyl)urea
Smiles: CC1C=C(C)C(=CC=1)OCC1=NN=C(NC(=O)NC2C=CC(C)=CC=2)S1
InChiKey: QUSAMXSWOZSTRQ-UHFFFAOYSA-N
InChi: InChI=1S/C19H20N4O2S/c1-12-4-7-15(8-5-12)20-18(24)21-19-23-22-17(26-19)11-25-16-9-6-13(2)10-14(16)3/h4-10H,11H2,1-3H3,(H2,20,21,23,24)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
cyt-PTPε Inhibitor-1 (Compound 62) is a potent cytosolic protein tyrosine phosphatase epsilon with anti-osteoclastic activity.
References:
- Ku B, et al. Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26(18):5204-5211.
Products are for research use only. Not for human use.
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