Aβ42-IN-1 free base


Catalog No. Size PriceQuantity
M13944-2 Contact sales@xcessbio.com for quotation $100

Description

Aβ42-IN-1 free base (compound 1v) is an orally active, high brain exposure γ-secretase modulator. Aβ42-IN-1 free base potently reduces Aβ42 levels with an IC50 value of 0.091 µM, and significantly reduces brain Aβ42 levels in mice. Aβ42-IN-1 free base is a promising compound for the treatment of Alzheimer’s disease.

Product information

CAS Number: 2434633-17-5

Molecular Weight: 462.54

Formula: C29H26N4O2

Chemical Name: 5-[8-({[1,1'-biphenyl]-4-yl}methoxy)-2-methylimidazo[1,2-a]pyridin-3-yl]-N-ethylpyridine-2-carboxamide

Smiles: CC1N=C2C(=CC=CN2C=1C1=CN=C(C=C1)C(=O)NCC)OCC1=CC=C(C=C1)C1=CC=CC=C1

InChiKey: VNNXRQLFCKSSMH-UHFFFAOYSA-N

InChi: InChI=1S/C29H26N4O2/c1-3-30-29(34)25-16-15-24(18-31-25)27-20(2)32-28-26(10-7-17-33(27)28)35-19-21-11-13-23(14-12-21)22-8-5-4-6-9-22/h4-18H,3,19H2,1-2H3,(H,30,34)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Aβ42-IN-1 free base treatment shows that the CLint value is 84.7 µL/min/mg protein.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed