Description
Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM). Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research.
Product information
CAS Number: 82425-45-4
Molecular Weight: 386.44
Formula: C22H26O6
Synonym:
(+)-Gomisin M2
Chemical Name: (9S,10R)-3,4,5-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.0²,⁷.0¹⁴,¹⁸]nonadeca-1(12),2,4,6,13,18-hexaen-19-ol
Smiles: C[C@H]1CC2=CC(OC)=C(OC)C(OC)=C2C2C(O)=C3OCOC3=CC=2C[C@H]1C
InChiKey: PDDXWOMYBJCSQB-NEPJUHHUSA-N
InChi: InChI=1S/C22H26O6/c1-11-6-13-9-16-20(28-10-27-16)19(23)17(13)18-14(7-12(11)2)8-15(24-3)21(25-4)22(18)26-5/h8-9,11-12,23H,6-7,10H2,1-5H3/t11-,12+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Min Chen, et al. Rubrisandrins A and B, Lignans and Related anti-HIV Compounds From Schisandra Rubriflora. J Nat Prod. 2006 Dec;69(12):1697-701.
- Hima Dhakal, et al. Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels. Front Pharmacol. 2019 Aug 2;10:869.
Products are for research use only. Not for human use.
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